Big Science Publishers
Serving Towards Science
Big Science Publishers
Serving Towards Science
Big Science Publishers
Serving Towards Science
OPEN ACCESS

Reviews in Pharmaceutical Sciences

Big Science Publishers LLP (registered under section 12(1) of the LLP act 2008) is a fully open access non-annual journal, publish high quality science-based review and research articles. Big Science Publishers also guide the young budding researchers, UG/PG students and scholars and other academic professional who wants to learn the manuscript writing.


Publications Easy under the aegis of Big Science Publishers provide the guidance and take the short tutorial classes to teach the basics to advanced level manuscript writing, supporting tools, finding the right journal, and other related advice to bring the quality manuscript.

Reviews in Pharmaceutical Sciences Cover

Reviews in Pharmaceutical Sciences

Big Science Publishers LLP (registered under section 12(1) of the LLP act 2008) is a fully open access non-annual journal, publish high quality science-based review and research articles. Big Science Publishers also guide the young budding researchers, UG/PG students and scholars and other academic professional who wants to learn the manuscript writing.


Publications Easy under the aegis of Big Science Publishers provide the guidance and take the short tutorial classes to teach the basics to advanced level manuscript writing, supporting tools, finding the right journal, and other related advice to bring the quality manuscript.

Home Articles Volume 2, Issue 2 Association between Alzheimer’s disease and Epilepsy...
Narrative Review

Association between Alzheimer’s disease and Epilepsy: A Narrative Review

Antil Chahat 1 , Bakthavatchalam Pugazhandhi 2
Volume 2 , Issue 2 , 2026-04 , Pages 01-20
Open Access
Open Access
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use. https://creativecommons.org/licenses/by/4.0/

History

Received: 2026-03-13
Accepted: 2026-04-02
Available Online: 2026-04-02

Abstract

Alzheimer’s disease (AD) is the most common neurodegenerative disorder and the leading cause of dementia worldwide. Increasing evidence suggests a significant association between Alzheimer’s disease and epileptic activity. Although seizures were historically considered a rare complication of Alzheimer’s disease, recent studies indicate that both clinical seizures and subclinical epileptiform activity occur more frequently in patients with AD than previously recognized. Neurodegenerative processes associated with Alzheimer’s disease, including amyloid-β accumulation, tau pathology, synaptic dysfunction, and neuronal network disruption, may increase neuronal hyperexcitability and contribute to seizure susceptibility. Several epidemiological and clinical studies have reported that individuals with Alzheimer’s disease have a significantly higher risk of developing epilepsy compared with age-matched individuals without dementia. Furthermore, epileptiform activity has been associated with accelerated cognitive decline and disease progression. This narrative review examines current scientific literature regarding the prevalence, underlying mechanisms, and clinical implications of epilepsy in patients with Alzheimer’s disease. Understanding the relationship between these two neurological conditions is important for improving early detection, clinical management, and long-term outcomes for affected patients.

Subject

Pharmacy

Article Type

Narrative Review

Keywords

Alzheimer’s disease epilepsy seizures neurodegenerati on amyloid beta epileptiform activity

Cite this Article

Formats

                                        
Actions
Download PDF
Metrics
2
Downloads
2
Views
Journal
Journal Reviews in Pharmaceutical Sciences
Volume Volume 2
Issue Issue 2
Year 2026

Purchase access plans

Select the plan that best fits your need

Loading plans...

Statistics: